In this module, you will learn about developmental processes that are key to the amazing phenomenon of tissue regeneration. Through hands-on laboratory sessions, you will have the thrilling opportunity to work with cutting-edge vertebrate or invertebrate models, delving into the fascinating role of signalling pathways in development and regeneration.

Prepare to be inspired as you learn how insights from human development are paving the way for groundbreaking medical advancements. Engage with experts from the Shrewsbury Assisted Conception Unit, who will share their exciting insights into tissue engineering and fertility treatments, which are impacting people's lives.

You will also unleash your creativity in the Bioreactors workshop, where cutting-edge technology meets innovative thinking in tissue engineering. With a rich mix of workshops, lectures, and hands-on laboratory experiences, you will come away with a profound understanding of developmental processes. Get ready for an adventure that combines science, innovation, and real-world applications!

In this module, you will embark on a learning journey through the forefront of molecular medicine! You will learn about transformative methodologies like CAR-T therapy, RNA interference (RNAi), CRISPR gene editing, monoclonal antibodies, and small-molecule inhibitors. You will explore fascinating developmental biology and reproductive medicine applications, featuring insightful talks from experts.

Not only will you enhance your knowledge, but you will also develop essential skills in experimental design and critical assessment. Participate in a hands-on CRISPR gRNA design workshop, where you'll sharpen your technical skills and engage in a practical laboratory experience focused on bacterial transformation used within academia and industry. This is not just a course—it's a gateway to the future of medicine! Get ready to be inspired and informed!

In this project-based module, you will investigate a gene of interest, unlocking its role within a specific differentiation pathway or regenerative process. You will use a bioinformatics-based approach to assess the conservation of your gene of interest across animals and assess the functional changes of importance. Additionally, you will Identify regulatory elements associated with the gene in your chosen species (e.g. human, mouse, chick, zebrafish, hydra). You will also identify expression patterns during development by assessing online RNA-Seq data.

Your hard work will culminate in a thoughtfully curated portfolio consisting of an introduction and analysis of your data. This is not just an assessment—it's an opportunity to showcase your understanding of genetics and its impact on life! Join us to learn about modelling molecular interactions in a supportive and collaborative environment.

Through project-based learning, with considerable opportunities for laboratory work, the module will provide you with the theoretical knowledge and practical laboratory experience in key techniques in molecular biology, with a focus on developing laboratory skills. Techniques explored during laboratory practicals may includet, bioinformatics, DNA extractions, DNA electrophoresis, nucleic acid quantitative and qualitative analysis techniques (eg, PCR), protein preparation and purification.

In this module, you will be introduced to scientific research. You will explore various types of research (descriptive, analytical & experimental), including pure versus applied ways of problem-solving. You will learn about the building blocks of scientific research: scientific language, ethical considerations and experimental design. You will also learn how research is funded. You will cover the following topics:

1. Research and data collection methods with an emphasis on experimental research (developing hypotheses, variables, controls, sample selection, design, validity)
2. The nature of the knowledge base and how research is communicated.
3. Advanced literature searching.
4. Critical appraisal of literature - primary and secondary literature
5. Developing a research project: identifying a topic area, devising specific questions, discovering what is already known (reviewing the literature), identifying gaps in knowledge, determining feasible ways to answer the questions.
6. Data analysis for research.

In this module, you will unlock an advanced understanding of the amazing potential of stem cell research and regenerative medicine to transform clinical conditions. You will explore innovative topics such as cutting-edge cell lines, intricate 3D organoids, dynamic explant cultures, and the incredible diversity of invertebrate models—from vibrant fish to agile amphibians and even birds and mammals!

This module promises theoretical insights and hands-on experiences that will ignite your passion for the field. You will engage with various models (fish, amphibians, avians, mammals), shaping the future of medicine and science and setting the stage for an exciting career or advanced study. Get ready for a journey that will challenge your intellect and fuel your curiosity as you learn to harness the power of stem cells!

You will have the opportunity to undertake an original research project in an area of relevance to your course and which interests you. The dissertation subject will be agreed with an appropriate supervisor and the module leader: you will prepare a detailed research proposal for evaluation prior to embarking on the research project. You will then communicate your project's outcomes in the most relevant forms.

Opportunities for skill development will be available throughout the year.